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Location: Moonachie, New Jersey
Ships to: US,
Item: 145348079342

All returns accepted:ReturnsNotAccepted
Expiration Date:Minimum 1 year
MPN:02301
Department:Adult,Unisex
Dosage:10 mg
When to Take:After Meal
Formulation:Bar,Capsule
Number of Pills:1
Ingredients:Apigenin,Theaflavin,Quercetin,Phosphatidylcholine,1-Deoxynojirimycin (DNJ)
Flavor:Apple
Life Extension:Life Extension
Volume:0.1 fl oz
Active Ingredients:Apigenin,Theaflavin,Quercetin,Phosphatidylcholine,1-Deoxynojirimycin (DNJ),Black Tea
Features:Vegeterian,Alcohol Free,Non-GMO
Main Purpose:Cardiovascular Health,General Wellness,Adrenal Support,Anti-Aging,Bodybuilding,Brain & Nervous System Health
Type:Vitamin
Item Weight:0.1 oz

Life Extension, Senolytic Activator - with Quercetin & Fisetin - For Immune Support, Anti-Aging & Longevity - Supports Systemic Rejuvenation - Non-GMO, Gluten-Free - 36 Vegetarian Capsules. Our Senolytic Activator® combines black tea theaflavins, the plant-derived flavonoid apigenin, and ultra-absorbable forms of the bio-flavonoids quercetin and fisetin to help manage senescent cell burden and promote systemic rejuvenation. Product DetailsCellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them.Senolytic compounds selectively target senescent cells.1 New research indicates that black tea theaflavins and quercetin target specific biological pathways, making it easier for the body to manage senescent cells.2-4Theaflavins reduce senescent cell burdenTheaflavins are compounds derived from Camellia sinensis (tea plant). These compounds have widespread health benefits, supporting healthy cell division and healthy inflammatory response.5,6New research indicates that theaflavins may be especially helpful for reducing senescent cell burden. In pre-clinical models, theaflavins helped powerfully inhibit the accumulation of particular cell senescence biomarkers.2Quercetin promotes cellular health and moreQuercetin supports endothelial and cardiovascular health, promotes healthy immune function and more.7,8 The value of quercetin has been recognized for some time. But its potential to meaningfully impact whole body rejuvenation is just starting to be uncovered through its senolytic activity. The discovery that quercetin is a senolytic compound has drawn significant attention to this innovative approach to combat aging.4Better absorption than standard types of quercetinStandard quercetin is hard to absorb. But this formulation features our new quercetin phytosome, a phospholipid sphere that encases the quercetin, aiding in its absorption and making it up to 50 times more bioavailable.Easy-to-absorb fisetin to boost longevity at the cellular levelFisetin is terrific for whole-body health. It’s a powerful senolytic compound, meaning it actively target senescent cells, the ones that no longer function optimally. Fisetin helps encourage the body’s natural pathways for clearing senescent cells, which allows healthy cells to flourish.9Another important aspect of cellular longevity is sirtuin function. Sirtuin proteins keep your cells performing at their best—but sirtuin activity declines with age.10 Fisetin has been shown in preclinical studies to encourage youthful, healthy sirtuin function.11-15But during digestion, much of fisetin is rapidly converted into other compounds by a process called conjugation. That’s why we protected fisetin by combining it with galactomannans, a type of fiber derived from fenugreek seed. Doing so makes it up to 25 times more readily available than standard fisetin.16 That means it circulates in your system longer and your body has more time to access fisetin’s many health benefits.ApigeninLife Extension has identified apigenin, a natural flavonoid, as a powerful addition to our Senolytic Activator® formula. Quercetin and theaflavins from black tea target senescent cells, but not all of them.The remaining senescent cells create compounds known collectively as Senescence Associated Secretory Phenotype, or SASP.17 Apigenin helps inhibit remaining senescent cells from making SASP to support cellular and tissue health—a critical aspect of healthy aging.18Convenient, once-weekly formulaFor those who aren’t keen on adding another supplement to their regimen, here’s good news: Senolytic research indicates that intermittent dosing in pre-clinical studies is effective at supporting healthspan.4 So, Senolytic Activator® instructions call for taking just three vegetarian capsules, once a week.Manage senescent cells, promote healthy cellular function and support overall longevity with Senolytic Activator®. LessThese statements have not been evaluated by the Food and Drug Administration.These products are not intended to diagnose, treat, cure, or prevent any disease.Supplement FactsServing Size 3 vegetarian capsulesServings Per Container 12Amount Per ServingBio-Fisetin Proprietary Blend312 mgProviding 18% fisetin (56 mg) [from wax tree extract (stem)], 35% galactomannans (109 mg) [from fenugreek (seed)] Theaflavins [from decaffeinated black tea extract (leaf)]275 mgBio-Quercetin phytosome 25 mg quercetin [from Japanese sophora concentrate (flower bud)], phosphatidylcholine complex [from sunflower])74 mgApigenin50 mgOther ingredients: vegetable cellulose (capsule), sunflower lecithin, microcrystalline cellulose, silica, vegetable stearate.Non-GMODosage and UseTake three (3) capsules once weekly, or as recommended by a healthcare practitioner.WarningsKEEP OUT OF REACH OF CHILDRENDO NOT EXCEED RECOMMENDED DOSEDo not purchase if outer seal is broken or damaged.When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

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